Motor disorders

Conditions affecting movement control, such as cerebral palsy, spasticity and dystonia, treated with physiotherapy, Botox or functional neurosurgery.

Pathway
Brain — neurosurgical
Reviewed by
Hussein Imran Mousa, consultant neurosurgeon
Reading time
2 min read
Last reviewed
March 2021

At a glance

What it is

Group of conditions with abnormal muscle tone or involuntary movement — cerebral palsy, spasticity, dystonia, ataxia. May be congenital, acquired, or progressive.

Typical signs

Stiffness, involuntary writhing or tremor, difficulty initiating movement, imbalance, or uncontrolled limb movements.

How we treat it

Physical therapy and stretching are foundation. Botulinum toxin for focal spasticity. Functional neurosurgery (selective dorsal rhizotomy, stereotactic lesioning) for severe, disabling cases.

What motor disorders are

Motor disorders span a spectrum from congenital cerebral palsy to acquired spasticity following stroke, spinal cord injury or brain trauma. The underlying problem is loss of normal inhibitory control over motor neurons, resulting in overactive reflexes, muscle tightness or involuntary movement.

What we see in clinic

2–3 per 1000

Children born with cerebral palsy

30%

Of stroke survivors develop spasticity within weeks

60–80%

Achieve functional improvement with botulinum toxin

Key facts

01 Spasticity is velocity-dependent stiffness — resistance increases with speed of stretch.
02 MRI or CT needed to rule out progressive structural lesions.
03 Botulinum toxin works within 1–2 weeks and lasts 3–4 months, requiring repeat injections.
04 Functional neurosurgery (dorsal rhizotomy, GPi deep brain stimulation) is reserved for severe cases refractory to conservative management.

How it is treated

Physical therapy is the foundation. Pharmacological and surgical options escalate with severity.

Physical therapy

First-line for all motor disorders

  • Stretching and positioning to prevent contracture
  • Gait training and balance exercises
  • Constraint-induced movement therapy (CIMT)

Botulinum toxin

Focal spasticity not responsive to therapy alone

  • Injection into overactive muscles
  • Blocks acetylcholine release, weakening muscle
  • Effect starts in 1–2 weeks, lasts 3–4 months

Oral medication

Generalised spasticity

  • Baclofen (GABA agonist)
  • Tizanidine (alpha-2 agonist)
  • Dantrolene (direct muscle relaxant)

Functional neurosurgery

Severe, disabling cases refractory to conservative therapy

  • Selective dorsal rhizotomy (SDR) in children with cerebral palsy
  • Stereotactic lesioning (pallidotomy, thalamotomy) for dystonia
  • Deep brain stimulation (GPi) for generalised dystonia

Related reading

Book a consultation

The secretary schedules first appointments during clinic hours; please have prior imaging, operative notes and a current medication list available at the time of the call.

This page provides general information about motor disorders and is not a substitute for individual medical assessment. If your symptoms are severe or worsening, contact a clinician promptly.